Patient with Chronic Myeloid Leukemia: A Case Study

نویسنده

  • Muhammad Zeeshan
چکیده

Introduction: Chronic myeloid leukemia abbreviated as CML is a type of myeloproliferative disease characterized by the increased and unregulated growth of predominantly myeloid cells in the bone marrow and the accumulation of these cells in the blood. It is a clonal bone marrow stem cell disorder in which a proliferation of mature granulocytes and their precursor is found. Case presentation: We report the case of 58-year-old Asian lady experiencing generalized body weakness, pallor, left upper abdominal pain and sudden weight loss of 5 kg within three weeks and a high blood pressure of 190/110. She has initially diagnosed splenomegaly and a mild heart attack. Various laboratory tests including complete blood count were conducted and the test results revealed a myeloproliferative disorder. The oncologist suggested bone marrow aspiration that led to a diagnosis of chronic myeloid leukemia. The disease was thought treated at an early stage but the case became complicated by previous untreated pathological conditions. Conclusion: Not all cases of CML are complicated in such a critical manner. Our report emphasizes on the fact of the need of good clinical evaluation by a qualified therapist and use of appropriate investigative studies is mandatory in order to secure patient from such a critical health condition. Citation: Zafar MZ (2017) Patient with Chronic Myeloid Leukemia: A Case Study. J Cancer Sci Ther 9: 635-636. doi:10.4172/1948-5956.1000485 J Cancer Sci Ther ISSN: 1948-5956 JCST, an open access journal Volume 9(9) 635-636 (2017) 636 remission. Hydroxyurea is equally effective but less mutagenic and has more favorable toxicity profile than Busulfan. Interferon-a can produce hematologic remission and can eliminate Philadelphia positive clone when assessed by classic cytogenetic. This drug is also used in combination with Cytarabine [8].

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تاریخ انتشار 2017